Population immunity dynamics, waning immunity trajectories, booster interval optimization, and coverage gap economics. Translate herd-level immunity into vaccine schedule and investment decisions.
Calculate the current effective immunity level of a population β accounting for vaccination coverage, vaccine efficacy, maternal immunity decay, and natural infection-derived immunity. The foundation of all herd immunity decisions.
Model how population immunity declines over time after vaccination. Waning immunity creates windows of epidemic vulnerability β calculate when a population falls below the herd immunity threshold and triggers the need for boosters.
Calculate the scientifically optimal booster vaccination interval to maintain population immunity above the herd immunity threshold continuously. Balances immunity duration against booster cost and operational feasibility.
Find the minimum cost-effective vaccination coverage level given Rβ, vaccine efficacy, and herd structure. Accounts for non-uniform mixing, age-structured populations, and the non-linear relationship between coverage and protection.
VS7 provides advanced herd immunity modeling calculators β population immunity level assessment, waning immunity trajectories, optimal booster interval calculation, and coverage optimization. These tools bridge the gap between individual vaccine efficacy data and population-level protection decisions.
For Rβ and SEIR models: VS5 Epidemiology β Β· For biosecurity complement: VS6 Biosecurity β Β· For mRNA vaccines: VS8 mRNA β
Research sources: Fine et al. (2011) Herd Immunity; Garnett (2005) vaccination program design; USDA-APHIS vaccination guidelines; Anderson & May (1991). VacStak β vacstak.com Β· Patent Pending Β· US App 63/970,943.